Polynucleotide Treatments at Reputation Aesthetics

Polynucleotides work differently to dermal fillers or skin boosters — rather than adding volume or focusing purely on hydration, they stimulate the skin’s natural regenerative processes. They support tissue repair, encourage collagen and elastin production, and improve overall skin quality for natural, long-lasting rejuvenation. They’re highly versatile, helping with fine lines, dehydration, dullness, skin laxity, dark circles, crepey skin and scarring.
 
Depending on the treatment area and individual concerns, polynucleotides can be administered using either a mesotherapy needle technique or via a cannula technique. During your consultation, we will discuss the most appropriate approach for your treatment plan.

I currently offer the following polynucleotide treatments:

  • Lumi-Eyes® – A regenerative treatment for the delicate eye area, improving hydration and elasticity while reducing tired, crepey skin and dark circles.
  • Vitaran® – Stimulates tissue repair and collagen production, ideal for fine lines, skin laxity and signs of ageing on the face, neck and eye area.
  • Plinest® – A premium treatment using highly purified polynucleotides to restore hydration, firmness and radiance for tired or ageing skin.
  • Plenhyage® – A next-generation treatment stimulating fibroblast activity for deep regeneration, particularly effective for early ageing and loss of elasticity.
 
If you’re unsure which polynucleotide treatment is right for you, I highly recommend booking a consultation beforehand so we can discuss your concerns in detail and create a treatment plan tailored specifically to your skin’s needs.

Results

Improved hydration & skin firmness.

Downtime

Minimal to none

Longevity

Up to 12-18 months.

Treatment Time

30 minutes

Your Treatment Journey

1

Enquiry

Begin by getting in touch to discuss your concerns and treatment goals. I'll respond directly, so you're speaking with me from the very first message rather than a booking team, and I'll make sure you're fully informed about the available options and the most appropriate approach for your needs. Whether you're considering a specific treatment or simply exploring what might suit you, I'm happy to answer your questions and offer honest, professional guidance.

2

Consultation

Your consultation is carried out by me personally, with plenty of time set aside for a thorough face-to-face discussion. We'll talk through your medical history, treatment concerns and desired outcomes, and I'll assess your suitability before creating a personalised treatment plan together. My focus throughout is on achieving safe, natural-looking results that are tailored specifically to you.

3

Treatment

Treatments take place within my private, luxury home studio, carried out with precision, care and close attention to detail. With over 15 years' experience across the beauty industry — including luxury cosmetics and advanced beauty education — I bring genuine expertise to every appointment. Using a personalised approach and a calm, relaxing environment, I prioritise your comfort and aim for natural-looking, confidence-boosting outcomes.

4

Post-Treatment Care

Your care continues after you leave the studio. You'll be given full aftercare advice to support the best possible results, and if you have any questions, concerns or notice anything that worries you afterwards, you can get in touch with me directly. Your comfort, safety and results matter to me throughout your entire treatment journey — not just on the day of your appointment."

Your Treatment Journey

1

Enquiry

Begin by getting in touch to discuss your concerns and treatment goals. I'll respond directly, so you're speaking with me from the very first message rather than a booking team, and I'll make sure you're fully informed about the available options and the most appropriate approach for your needs. Whether you're considering a specific treatment or simply exploring what might suit you, I'm happy to answer your questions and offer honest, professional guidance.

2

Consultation

Your consultation is carried out by me personally, with plenty of time set aside for a thorough face-to-face discussion. We'll talk through your medical history, treatment concerns and desired outcomes, and I'll assess your suitability before creating a personalised treatment plan together. My focus throughout is on achieving safe, natural-looking results that are tailored specifically to you.

3

Treatment

Treatments take place within my private, luxury home studio, carried out with precision, care and close attention to detail. With over 15 years' experience across the beauty industry — including luxury cosmetics and advanced beauty education — I bring genuine expertise to every appointment. Using a personalised approach and a calm, relaxing environment, I prioritise your comfort and aim for natural-looking, confidence-boosting outcomes.

4

Post-Treatment Care

Your care continues after you leave the studio. You'll be given full aftercare advice to support the best possible results, and if you have any questions, concerns or notice anything that worries you afterwards, you can get in touch with me directly. Your comfort, safety and results matter to me throughout your entire treatment journey — not just on the day of your appointment."

Message from Megan

I believe beauty should feel personal, not clinical. My aim is to help every client feel refreshed, confident and completely like themselves – never overdone. Every treatment I carry out is tailored to you, delivered with genuine care, attention to detail and a real passion for helping you feel comfortable in your own skin. My commitment is to natural-looking results in a calm, private setting, so you leave feeling valued, cared for and glowing from the inside out.

Megan Allen | Founder & Director
Advanced Aesthetics Practitioner

Polynucleotide FAQs

What are polynucleotides?
Polynucleotides are advanced regenerative injectable treatments that work by stimulating the skin’s natural repair and renewal processes. They help improve skin quality by encouraging collagen and elastin production, increasing hydration and supporting tissueregeneration.
 
Whilst skin boosters primarily focus on improving hydration, polynucleotides work at a deeper regenerative level by repairing and strengthening the skin. They improve overall skin quality, support tissue healing and stimulate collagen production, making theman excellent option for long-term skin rejuvenation.
 
Polynucleotides can help improve fine lines, skin laxity, dehydration, dullness, crepey skin, dark circles, scarring and overall skin quality. They are suitable for clients wanting natural-looking rejuvenation and healthier, stronger skin.
 
Depending on the treatment area and your individual needs, polynucleotides can be administered using either a mesotherapy needle technique or a cannula technique. This will be discussed during your consultation and tailored to your treatment plan.
 
The most suitable treatment depends on your concerns and desired outcomes. During your consultation, we will assess your skin and create a personalised treatment plan together.
 
Most appointments take approximately 30–45 minutes, including consultation, preparation and treatment.
 
Most clients achieve optimal results following a course of treatments, usually consisting of two to three sessions depending on the product selected, whether this is Lumi-Eyes®, Vitaran®, Plinest® or Plenhyage®, and your individual concerns. Maintenance treatments can then be carried out to prolong your results.
 
Many clients notice improvements in hydration and skin quality within the first few weeks. However, because polynucleotides stimulate the skin’s natural regeneration processes, improvements continue to develop over several weeks and months.
 
Downtime is generally minimal. Mild redness, swelling, tenderness and small bumps at the injection sites are common and usually settle naturally within a few hours to a few days.
 
Absolutely. Polynucleotides do not add volume or alter your facial features. Their purpose is to improve the health and quality of your skin, leaving you looking refreshed, rejuvenated and naturally radiant.
 
No. Polynucleotide treatments are not recommended during pregnancy or while breastfeeding.
 

Before Your Appointment

To ensure your treatment experience is as comfortable and enjoyable as possible, please take a moment to read the following pre-treatment advice.
 
  • Don’t worry if you arrive wearing makeup. All aesthetic appointments begin with a luxury cleanse of the treatment area, so there is no need to arrive makeup-free. This is your time to relax and be completely looked after from the moment you arrive.
  • Please attend your appointment feeling well and inform me of any changes to your medical history, medications or health since booking.
  • Stay well hydrated in the days leading up to your appointment. Drinking plenty of water and ensuring you are adequately hydrated supports overall skin health and may aid the healing and regenerative processes following treatment.
  • Avoid alcohol for at least 24 hours before treatment where possible, as this can increase the likelihood of bruising and swelling.
  • If possible, avoid taking blood-thinning medications or supplements, such as aspirin, ibuprofen, fish oils and certain herbal supplements, unless they have been prescribed by your doctor.
  • Avoid booking treatment immediately before an important event, holiday or special occasion, as mild swelling or bruising can occasionally occur.
  • If you have an active skin infection, cold sore, are feeling unwell or have recently undergone another aesthetic treatment, please get in touch prior to your appointment.
  • Polynucleotide treatments are not recommended during pregnancy or while breastfeeding.
  • If you are unsure which treatment is right for you, I recommend booking a consultation beforehand so we can discuss your concerns and create a personalised treatment plan together.
 
My aim is to provide a calm, luxurious and welcoming experience where you feel fully informed, comfortable and confident throughout your appointment.

Aftercare Advice

Following your polynucleotide treatment, it is important to follow the aftercare advice below to support healing and achieve the best possible results.
 
  • Avoid touching, rubbing or applying pressure to the treated areas for at least 24 hours.
  • Avoid strenuous exercise, excessive heat, saunas, steam rooms and hot tubs for 24–48 hours following treatment.
  • Avoid alcohol for 24 hours, as this may increase swelling and bruising.
  • Avoid makeup on the treated area for at least 12 hours, unless otherwise advised.
  • Continue to drink plenty of water and keep yourself well hydrated following treatment. Polynucleotides work by supporting tissue repair and regeneration, and maintaining good hydration helps support your skin’s natural healing processes.
  • Mild redness, tenderness, swelling and small bumps at the injection sites are common and usually settle naturally within a few hours to a few days.
  • Avoid further facial treatments, exfoliating products and active skincare ingredients until the skin has fully recovered.
  • Keep the treated area clean and follow any individual aftercare advice provided during your appointment.
  • Results develop gradually as collagen production and tissue regeneration take place, with improvements continuing to develop over several weeks and months.
  • If you have any concerns following treatment or experience anything that worries you, please contact me. Your safety, comfort and aftercare are extremely important to me.
 
My goal is to help you achieve healthier, stronger and naturally rejuvenated skin while ensuring you feel supported and cared for throughout your entire treatment journey.